Journalist

Park boram
  • Celltrion Launches Autoimmune Drug Aptozma in Japan as First Mover
    Celltrion Launches Autoimmune Drug Aptozma in Japan as First Mover Celltrion said April 28 that it has launched Aptozma (tocilizumab), an autoimmune disease treatment, in Japan as a first mover. The launch comes about seven months after the drug won marketing approval from Japan’s Ministry of Health, Labour and Welfare in September. Celltrion said it has secured approvals for key indications including rheumatoid arthritis, juvenile idiopathic arthritis, Castleman disease and cytokine release syndrome. Celltrion’s Japan unit plans to supply the product through a direct sales system. The company said it aims to speed market adoption by drawing on sales capabilities and supply experience built through its existing autoimmune treatments. Ahead of the launch, the company provided scientific information to clinicians and shared clinical data at the 70th Annual Meeting of the Japan College of Rheumatology to raise awareness of the product. Celltrion said it has established a stable foothold in Japan’s autoimmune disease market. Remsima and Yuflyma hold 44% and 19% market share, respectively, and remain among the top prescribed biosimilars, while Stekima continues to grow. With Aptozma, the company’s local portfolio has expanded to four products. Celltrion said it plans to maximize synergies across its products and step up marketing to medical institutions. It said portfolio expansion is expected to continue, with Omliclo targeted for launch in the second half of the year and Remsima SC also being prepared for entry into the Japanese market.* This article has been translated by AI. 2026-04-28 11:30:13
  • Cha Biotech Partners With Miltenyi Biotec to Develop Allogeneic CAR-NK Cancer Therapy
    Cha Biotech Partners With Miltenyi Biotec to Develop Allogeneic CAR-NK Cancer Therapy Cha Biotech said on the 28th it will work with Miltenyi Biotec, a global cell and gene therapy company, to develop an allogeneic chimeric antigen receptor-expressing natural killer cell (CAR-NK) therapy. Under the collaboration, Miltenyi Biotec will produce lentiviral vectors and supply them to Cha Biotech. The company said Miltenyi brings expertise including its BaEV platform, designed to improve gene-delivery efficiency while lowering manufacturing costs. The BaEV platform targets ASCT1 and ASCT2 receptors expressed on NK cells to boost gene transfer efficiency. Cha Biotech plans to use the vectors to develop a CAR-NK-based anticancer cell therapy, CHACAR-NK-201. Based on its in-house NK cell culture technology, the company said it is expanding research in solid tumors including liver cancer, glioblastoma and triple-negative breast cancer. A Cha Biotech official said CAR-NK therapies are viewed as next-generation immune cell treatments because they can be mass-produced using NK cells from healthy donors, offering advantages in accessibility and cost compared with CAR-T therapies that require patient-specific manufacturing. Separately, Cha Biotech said it is also working with Miltenyi Biotec Korea to develop an automated process for mass production of allogeneic CAR-NK therapies and to strengthen manufacturing capabilities that meet global standards. * This article has been translated by AI. 2026-04-28 11:27:16
  • JW Pharmaceutical Expands License-In Drug Strategy With VC Acquisition
    JW Pharmaceutical Expands License-In Drug Strategy With VC Acquisition JW Pharmaceutical is doubling down on a “license-in” strategy—bringing in drug candidates developed elsewhere and handling development and regulatory approval in South Korea—while widening its reach by adding venture investment, industry officials said. According to the industry on the 27th, JW Holdings, the group’s holding company, recently acquired venture capital firm Solidus Investment and made it a subsidiary. The deal was valued at 30.6 billion won. Solidus Investment is a biotech-focused VC with investments that include Alteogen, Orum Therapeutics and OliX. Venture capital firms review a wide range of biotech companies and assess the commercial potential of their technologies. By bringing a VC in-house, the group aims to secure promising pipelines early and then use its research and development capabilities to move them into clinical trials and commercialization. A JW Pharmaceutical official said the company concluded it would be more efficient to identify partners for joint research through a VC than to invest directly in biotech firms, calling it part of an effort to expand open innovation. The company has continued to sign license-in deals structured to secure direct marketing rights rather than co-promotion. The approach requires higher upfront costs but allows stable sales without paying commissions. JW Pharmaceutical said it has used the strategy to establish high-revenue products including the cholesterol drug “Livalo family,” the hemophilia treatment “Hemlibra” and the arthritis drug “Actemra.” More recently, JW Pharmaceutical signed an exclusive South Korea license agreement with China’s Gan & Lee Pharmaceuticals for the glucagon-like peptide-1 (GLP-1) receptor agonist “bofanglutide.” The total contract value is $81.10 million (about 119.8 billion won). Bofanglutide is being developed as a subcutaneous injection given once every two weeks, with dosing convenience positioned as a differentiator. The company plans to begin a domestic Phase 3 trial in the second half of this year for obesity and Type 2 diabetes. The strategy is to respond early to the metabolic disease treatment market by licensing in a candidate that is already well advanced in development. License-in deals are difficult to turn into results without strong in-house R&D. On the 23rd, JW Pharmaceutical completed dosing the last patient in a multinational Phase 3 trial of its gout candidate “epaminurad.” Epaminurad is an oral new drug candidate being developed for hyperuricemia and gout, conditions marked by abnormally high uric acid levels in the blood. Trials were conducted in five Asian countries including South Korea, and the company expects to produce a results report within the year after the final dosing in Malaysia. The company said it aims to develop the drug as a “best-in-class” therapy. JW Pharmaceutical’s R&D spending ratio last year was 14%, the biggest increase among major drugmakers. It exceeded the average for the top 10 pharmaceutical companies as of 2024 (11.3%), and R&D spending reached 107.9 billion won, topping 100 billion won for the first time in the company’s history. An industry official said JW Pharmaceutical is placing more weight on building a medium- to long-term growth base than on short-term results, adding that it is likely to continue building a stable profit structure on the license-in strategy it has pursued for years.* This article has been translated by AI. 2026-04-27 18:31:25
  • JW Pharmaceutical Completes Phase 3 Dosing for Gout Drug Candidate; Results Due by Year-End
    JW Pharmaceutical Completes Phase 3 Dosing for Gout Drug Candidate; Results Due by Year-End JW Pharmaceutical completes Phase 3 dosing for gout drug candidate epaminurad; results due by year-end JW Pharmaceutical said April 27 it has completed dosing the last patient in a multinational Phase 3 trial of its gout treatment candidate epaminurad (URC102). Epaminurad is an oral uricosuric drug designed to selectively inhibit hURAT1, promoting uric acid excretion. The company is developing it for hyperuricemia and gout, conditions marked by abnormally high blood uric acid levels. JW Pharmaceutical said it has been running the Phase 3 study in five Asian countries, including South Korea, after receiving approval for the trial plan (IND) from the Ministry of Food and Drug Safety in 2022. The study was designed to compare uric-acid lowering effects and safety against the existing treatment febuxostat, and the final patient was dosed in Malaysia. In an earlier Phase 2 trial, epaminurad met key efficacy endpoints and showed safety and tolerability, the company said. JW Pharmaceutical also said it recently secured a U.S. patent from the U.S. Patent and Trademark Office covering dosing and administration, extending U.S. exclusivity to 2038. The company plans to produce a clinical study report by the end of this year after follow-up and data analysis. HK inno.N expands collaboration to develop next-generation obesity drug using AI platform HK inno.N said April 27 it signed a joint research and development agreement with Atomatrix to develop a next-generation obesity treatment. The partners said they will use an artificial intelligence and computer-simulation drug design platform to identify small-molecule candidates with new mechanisms intended to address limitations of incretin-based obesity drugs, including GLP-1 receptor agonists. Under the agreement, HK inno.N will synthesize compounds and conduct biological evaluations to verify efficacy and safety, while Atomatrix will design and screen candidates using its platform, CANDDIE. CANDDIE applies molecular dynamics-based analysis to predict not only binding stability between target proteins and candidates but also drug-response effects after binding, the companies said. HK inno.N cited its commercialization track record with the gastroesophageal reflux disease drug K-CAB and said it aims to expand competitiveness in the obesity treatment market. SK Chemicals holds spring outing volunteer program with seniors to boost intergenerational ties SK Chemicals said April 27 it held a family volunteer program, “Norang, Spring,” bringing together seniors and employees’ families ahead of Family Month in May. The company said it is emphasizing hands-on volunteering, not only donations, as part of its social responsibility efforts. The event was organized with the Unjeong Comprehensive Social Welfare Center in Paju and travel agency Yellow Balloon, and took place around Insadong and Jongno in central Seoul. The program paired seniors living alone with SK group employees’ families for cultural activities and an outing in the city. About 50 people, including families from SK affiliates and seniors using the welfare center, took part, the company said. Activities included making rice cakes, visiting a museum, touring the city by bus and visiting the Cheong Wa Dae Sarangchae. Kolon Life Science publishes preclinical results for anticancer gene therapy candidate KLS-3021 Kolon Life Science said April 27 that preclinical findings on its anticancer gene therapy candidate KLS-3021 for cutaneous squamous cell carcinoma, or cSCC, were published in the international journal Molecular Therapy Oncology (impact factor 5.3). KLS-3021 is a candidate built on a recombinant vaccinia virus engineered for greater selectivity for cancer cells and loaded with therapeutic genes PH-20, IL-12 and sPD1-Fc. It is designed to lyse tumors, break down extracellular matrix within tumors and trigger immune responses, the company said. In the study, KLS-3021 showed higher selective cytotoxicity and viral replication in cancer cells than in normal cells, and the virus’s ability to replicate inside tumors suggested potential for additional therapeutic effects, the company said. In a metastatic model, viral spread was also confirmed at metastatic sites. The company said a single injection could allow the drug to circulate and target cancer cells at distant sites, raising the potential for treating metastatic cancer. The study also observed changes in the tumor microenvironment, including hyaluronic acid degradation, increased immune-cell infiltration and immunogenic cell death, suggesting it may be able to address physical and immunological barriers at the same time, the company said.* This article has been translated by AI. 2026-04-27 18:17:37
  • Dong-A Socio Holdings Q1 Operating Profit Falls 6% Despite Revenue Growth
    Dong-A Socio Holdings Q1 Operating Profit Falls 6% Despite Revenue Growth Dong-A Socio Holdings said profitability weakened in the first quarter as higher costs offset revenue growth. The company said on the 27th that, on a consolidated basis, first-quarter revenue rose 6.9% from a year earlier to 351.0 billion won, while operating profit fell 6.0% to 19.1 billion won. The company attributed the decline in operating profit to higher cost ratios at its operating subsidiaries, citing the impact of external conditions. Healthcare unit Dong-A Pharmaceutical posted revenue of 188.0 billion won, up 10.5%, driven by growth in Bacchus and over-the-counter drug sales. Operating profit rose 22.1% to 20.6 billion won. Bacchus and OTC products grew 11.0% and 17.3%, respectively, while health functional foods slipped 2.1%. STgen Bio, a contract manufacturer of biopharmaceuticals, reported revenue of 18.0 billion won, down 5.7%. Operating profit plunged 89.1% to 200 million won due to fixed-cost burdens. The company said results can vary by quarter depending on customer order schedules, adding that planned annual orders totaling 21.1 billion won are proceeding as scheduled. Logistics unit Yongma Logistics recorded revenue of 110.6 billion won, up 9.6% from a year earlier, helped by new client wins. Operating profit, however, fell 10.4% to 3.8 billion won due to higher fuel costs and rising prices for logistics materials.* This article has been translated by AI. 2026-04-27 16:19:02
  • Samsung Medical Center Launches Smart Patient Rooms to Boost Safety and Efficiency
    Samsung Medical Center Launches Smart Patient Rooms to Boost Safety and Efficiency Samsung Medical Center said on the 27th it has introduced “smart patient rooms” as part of a patient-centered overhaul aimed at improving safety, convenience and staff efficiency. The hospital said the rollout is part of a mid- to long-term strategy to move beyond isolated technology upgrades and transition to an advanced, intelligent hospital model. The hospital has worked since 2020 to improve inpatient-room environments. Based on patient satisfaction surveys, it formed a “Future Hospital TF” to define the smart-room concept and develop an operating system for it. Lee Sang-cheol, head of the Heart and Brain Vascular Hospital and a professor of cardiology, said the smart rooms focus on linking patient safety and the overall treatment experience “into a single flow,” rather than simply adding new devices. The rooms use a facial-recognition entry system to strengthen security and ease of access. Patients can use an in-room tablet to control lighting and temperature, check key information in real time — including test results, appointment schedules and meal changes — and communicate with medical staff through chat, voice calls and video calls. Monitoring has also been expanded. Wearable devices allow real-time checks of vital signs such as blood pressure, electrocardiograms and oxygen saturation, enabling faster responses to warning signs. Radar-based sensors installed in patient rooms and bathrooms are designed to detect risky situations early. For staff, the hospital said efficiency improves when an artificial intelligence avatar generates education videos after clinicians enter disease-education content, reducing the need for repeated explanations. Patients can receive tailored education in their rooms. Samsung Medical Center said it will review operating results and consider expanding the system across the hospital and applying additional AI technologies.* This article has been translated by AI. 2026-04-27 10:51:05
  • Korean Drugmakers Rush Into Clinical Trials for Next-Generation ADC Cancer Drugs
    Korean Drugmakers Rush Into Clinical Trials for Next-Generation ADC Cancer Drugs South Korea’s pharmaceutical and biotech companies are moving aggressively into clinical development of antibody-drug conjugates, or ADCs, as global drugmakers pour massive investment into the fast-heating field. Several Korean firms have now advanced candidates to the patient-dosing stage, intensifying competition to develop next-generation cancer therapies. Industry officials said ADCs combine an antibody’s ability to target tumors with the cancer-killing effect of a cytotoxic drug. By linking the drug to an antibody, the therapy is designed to deliver treatment selectively to cancer cells, potentially reducing toxicity compared with conventional chemotherapy while improving effectiveness. Celltrion is accelerating development with multiple programs. After securing Finobio’s platform technology, PINOT-ADC, in 2022, it advanced three ADC cancer candidates to patient dosing. The three pipelines — CT-P70, CT-P71 and CT-P73 — received U.S. Food and Drug Administration approval for Phase 1 investigational new drug applications last year. CT-P73 began dosing patients in the first quarter of this year, while CT-P70 and CT-P71 started dosing in the second half of last year. CT-P70 and CT-P71 also received FDA fast-track designation, the company said. Samsung Bioepis, long focused on biosimilars, has entered new-drug development and moved into ADCs. After signing a joint research and technology licensing deal with Intocell in December 2023, it launched a global Phase 1 trial of its first new-drug pipeline, SBE303. Preclinical results disclosed at the American Association for Cancer Research meeting, AACR 2026, showed SBE303 improved tumor-cell binding specificity and intracellular drug-delivery efficiency compared with existing nectin-4 targeted therapies, the company said. It also reported no observed safety signals such as interstitial lung disease, or ILD. Chong Kun Dang, known for a strong oncology portfolio, is also expanding into biologic drugs through ADC development. After licensing platform technology from Dutch company Synaffix in 2023, it has been developing CKD-703, a c-Met-targeting ADC. In a global Phase 1/2a trial, the company has begun enrolling its first patient in the United States. The study targets patients with solid tumors including non-small cell lung cancer, or NSCLC, and is being conducted at about 12 sites in South Korea and the United States. The company said it has also received clinical approval in South Korea and expects patient enrollment there in the first half of the year, with plans to expand to Europe and other countries. According to market research firm Mordor Intelligence, the ADC market is projected to grow from about $20 billion this year to $70 billion by 2031. Expectations are rising that if ADCs expand into first-line treatment for major cancers, the number of patients and duration of dosing could increase sharply. To date, 15 ADC therapies have received FDA approval. One industry official said ADCs are being valued highly because of their potential expansion into first-line treatment. “ADCs are emerging as a mainstream approach in the oncology market, so the market is likely to grow even larger,” the official said.* This article has been translated by AI. 2026-04-26 13:27:18
  • Dong-A ST, Aptis and Celltrion Pharm present next-generation cancer R&D at AACR 2026
    Dong-A ST, Aptis and Celltrion Pharm present next-generation cancer R&D at AACR 2026 Dong-A ST and Aptis present next-generation cancer pipeline at AACR Dong-A ST said April 24 that it and its subsidiary Aptis, an antibody-drug conjugate (ADC) specialist, presented 10 preclinical studies on next-generation cancer pipeline programs at the American Association for Cancer Research meeting (AACR 2026). The presentations included results on a PARP7 inhibitor, EGFR-targeted protein degraders and bispecific antibody ADCs. Dong-A ST’s PARP7 inhibitor candidate SC5024 showed a “dual anti-cancer mechanism” in preclinical testing, inducing both tumor-cell suppression and immune activation, the company said, suggesting potential for use alone or in combination. It also presented an anti-cancer strategy using EGFR-targeted protein degraders SC3613 and SC3499, co-developed with HK inno.N, designed to selectively eliminate mutant EGFR proteins. The companies also outlined a treatment strategy based on a bispecific ADC platform. Bispecific ADCs combining Dong-A ST’s bispecific antibody platform with Aptis’ linker technology — Nectin-4×PD-L1, HER2×AXL and Claudin18.2×HER2 — were analyzed using omics and AI based on patient-derived cancer cells, and were presented as having potential to address drug resistance and tumor heterogeneity. Oh Yun-seok, Dong-A ST vice president and chief scientific officer, and Choi Hyeong-seok, president of Aptis, introduced key pipeline programs and research strategy at the meeting and discussed possible collaboration with global drugmakers, the companies said. Celltrion Pharm presents results for two dual-payload ADC programs at AACR 2026 Celltrion Pharm said April 24 it presented research results at AACR 2026 in San Diego on two new pipeline candidates based on its dual-payload ADC platform. The company said it first unveiled the platform at AACR 2025 with its HER2-targeting candidate CTPH-02, which links two payloads with different mechanisms of action to a single antibody. The platform showed strong cytotoxicity not only in cell lines with high HER2 expression but also in those with low expression, it said. Celltrion Pharm also presented CTPH-08, a candidate targeting FRα, applying the platform to a new target. The company said the data supported the scalability of the dual-payload approach and suggested potential to address tumor heterogeneity and drug resistance. Hyundai Bioscience joins Vietnam economic delegation, signs MOU with local drugmaker Hyundai Bioscience said April 24 it signed a broad memorandum of understanding with Vietnamese pharmaceutical company Vepaco covering approval, importation, distribution and supply of an antiviral drug in Vietnam. The company said the signing took place during a forum attended by key figures from both countries to discuss economic cooperation, with South Korea’s minister of trade, industry and energy and Vietnam’s minister of finance present. Hyundai Bioscience said the agreement sets out basic directions and a roadmap for jointly pursuing regulatory approvals and supply projects. The companies plan to form an executive-level working group to hold regular meetings and to detail cooperation tasks, including patient linkage using local medical and pharmacy networks. Hyundai Bioscience said it aims to link dengue clinical work in Vietnam with approval and commercialization strategies.* This article has been translated by AI. 2026-04-24 17:59:24
  • South Korea Finds 32 Syringe Sellers Violating Anti-Hoarding Rules, Launches Ongoing Checks
    South Korea Finds 32 Syringe Sellers Violating Anti-Hoarding Rules, Launches Ongoing Checks The Ministry of Food and Drug Safety said April 24 it found 32 companies nationwide that violated a government notice banning syringe hoarding, following a special inspection aimed at stabilizing distribution. The ministry said it will file complaints and issue corrective orders against the companies and will continue to monitor compliance through follow-up inspections. The ministry disclosed the results at a briefing at its Seoul regional office in Yangcheon-gu. The first round of inspections, conducted from April 20 to 22, targeted sellers with low sales compared with incoming stock, unusually large inventories, supplies concentrated on specific buyers, or sales at high prices. Inspectors found four companies that stored syringes for at least five days in excess of 150% of their monthly average sales volume, and 30 companies that supplied excessive quantities to the same buyers. Two companies were found to have committed both types of violations. One company was caught holding about 130,000 syringes for more than five days as inventory far exceeded its sales volume. The ministry ordered the excess stock to be shipped within 24 hours to online shopping malls experiencing shortages. Another company was found to have supplied about 620,000 syringes — up to 59 times its monthly average sales volume — to 33 repeat buyers, including specific medical institutions and sellers. Kim Myeong-ho, director general of the ministry’s Medical Device Safety Bureau, said the ministry will file complaints and issue corrective orders, and will immediately pursue additional complaints if violations are confirmed again during re-inspections. The ministry said syringe production remains at normal levels compared with last year and that supply is not a problem. It said daily output averaged about 3.6 million units last year and has risen to more than 4.5 million this year. The ministry said it believes anxiety over recent supply instability led to hoarding at some points in the distribution chain. The ministry said it is collecting data from about 1,000 companies and analyzing distribution routes to check whether supplies are being concentrated at specific firms. It also said it is responding quickly to on-site enforcement through a reporting center where the public can report syringe hoarding. The ministry said it will strengthen monitoring across manufacturing and distribution and continue cracking down on actions that disrupt distribution order and risk supply disruptions.* This article has been translated by AI. 2026-04-24 17:57:10
  • Celltrion Starts Patient Dosing for Three ADC Cancer Drug Candidates
    Celltrion Starts Patient Dosing for Three ADC Cancer Drug Candidates Celltrion begins patient dosing for all three ADC cancer drug candidates Celltrion said April 23 that all three of its antibody-drug conjugate (ADC)-based cancer drug candidates have entered the patient-dosing stage. The candidates now being dosed are CT‑P70, CT‑P71 and CT‑P73. All three received U.S. Food and Drug Administration approval last year for investigational new drug (IND) applications for Phase 1 trials, the company said. Patient dosing for CT‑P70 and CT‑P71 began in the second half of last year, and CT‑P73 dosing began in the first quarter of this year. Celltrion said preclinical studies confirmed the candidates’ mechanisms of action and safety. In Phase 1, it plans to evaluate dose-by-dose safety and pharmacokinetic characteristics. The company is also developing a multispecific antibody candidate, CT‑P72. It is currently recruiting patients and could begin dosing the first patient as early as next month. Korea Pharmaceutical and Bio-Pharma Association adds hands-on training on U.S. life sciences patents The Korea Pharmaceutical and Bio-Pharma Association said April 23 it will launch a practical training course on responding to U.S. life sciences patent issues on June 12 at the association’s fourth-floor auditorium. The association said the program is designed to strengthen companies’ ability to manage U.S. patent risks that can arise during global expansion, including technology licensing, partnering and overseas clinical trials. It cited cases in which negotiations collapsed after businesses moved forward without freedom-to-operate (FTO) analysis, or deals were delayed during due diligence because of intellectual property issues. The course will have three sessions: the reality of U.S. life sciences patent disputes and core FTO concepts and practical considerations; U.S. patent avoidance strategies and global dispute trends; and global IP strategy and commercialization preparation at the research and development stage. The lecture will be led by attorney Nam In-young, a New York and California-licensed lawyer and U.S. patent litigation specialist, the association said. The program is aimed at R&D and IP staff, business development and corporate planning personnel, and executives and decision-makers at life sciences companies considering or pursuing entry into the U.S. market. Enrollment will be capped at 50 participants. Handok holds plogging cleanup campaign in Busan with employees Handok said April 23 that it held an environmental cleanup “plogging” volunteer event with employees on April 22 around Busan Citizens Park. The company said the campaign, titled “Pick up for me, pick up for Earth,” was organized with the Busan Volunteer Center to mark Earth Day on April 22. It also aimed to spruce up the area ahead of the 20th National Para Student Sports Games and the 55th National Youth Sports Games. About 30 Handok employees, including sales staff working in Busan, took part, the company said. It plans to continue individual plogging through May 24 using the Busan Volunteer Bank application. Chong Kun Dang Gochon Foundation names three artists for 2026 program, expands support The Chong Kun Dang Gochon Foundation said April 23 it selected three artists — Kim Myeong-chan, Park Geurim and Yeom Ji-hee — as this year’s artists and held a certificate presentation ceremony April 22 at Chong Kun Dang’s headquarters in Chungjeong-ro, Seoul. The foundation said the artists were recognized for experimentation and growth potential within contemporary painting. The selections were made through a closed review by a panel of art experts. Each artist will receive 10 million won a year in creation grants for three years, and in the final year will be given an opportunity to present results through a curated exhibition, the foundation said. The “Chong Kun Dang Gochon Art Award” is a cultural and arts social contribution program launched at the suggestion of Chairman Lee Jang-han to support emerging artists with growth potential. Since 2012, it has been run with Chong Kun Dang Holdings, the Korea Mecenat Association and Art Space Huga, and has discovered and supported a total of 45 artists, the foundation said.* This article has been translated by AI. 2026-04-23 18:10:18