Chinese scientist maps important genetic machine
By Park Sae-jin
Posted : September 1, 2015, 16:07
Updated : September 1, 2015, 16:07
Shi Yigong, dean of the School of Life Sciences at Tsinghua University, announced the findings following the publication of two papers in the U.S. journal Science.
Shi's lab used the latest cryo-EM technology, which is used to study the architecture of cells, to map the structure of the spliceosome at atomic resolution. His findings improved the resolution by almost eight times, he said.
"Mapping spliceosome has been extremely difficult because it is very dynamic, and exists in a series of distinct conformations, with different components," Shi said.
By Ruchi Singh